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教授研究员

刘勇 教授
发布日期:2021-04-30 作者:刘勇

刘勇

教授

博士研究生

E-mail

lycc2010@126.com

云南省昆明市呈贡区大学城东外环(650500

  

刘勇,男,工学博士,教授,研究方向为功能材料与生态毒理学。主要开发生态修复新技术实现对生态相关成分的识别和检测;构建生态与环境相关材料在生态环境及其生物体内的应用研究。近5年来第一作者或通讯作者发表SCI论文20余篇:其中JCR一区TOP,包括中科院一区SCI论文18篇。其中,IF>202, IF>105篇,IF>611篇。主持国家自然科学基金项目2项(面上和青年),山东省自然科学基金项目1项,云南省高层次人才项目1项,云南省社会发展专项1项,横向课题1项。授权发明专利3项。成果转化1项。

一、教育背景

2011/09 – 2014/06   山东大学        工学 博士

2008/09 – 2011/06   西北师范大学      理学 硕士

2004/09 – 2008/06    西安文理学院     理学 学士

二、工作经历

2020/12 -至今,云南大学生态与环境学院湖泊院   教授

2014/08 -2020/11  济南大学光功能材料与成像研究院  讲师 副教授

三、教学工作

《环境材料学》、《物理化学》、《野外综合实习》

四、研究领域

●  生态毒性研究

  开发生态修复新技术实现对生态相关成分的识别和检测;土壤,湖泊等环境DNA的提取和检测,以及真核细胞内核酸 DNARNA)的检测,进一步研究污染物对生物体的生态毒理性。

●  污染物及活性分子检测技术研发

主要构建生态毒素与环境相关探针在生态环境及其生物体内的应用研究。基于此研究对环境毒素以及易接触人群的健康评价。

五、承担项目

1. 云南省社会发展专项课题:基于湖泊治理与流域生态修复的核心关键技术研发; 项目编号:202103AC100001100万,2021/04-2024/04; 在研,主持。

2. 国家自然科学基金面上项目:构建新型近红外荧光探针监测癌细胞和肿瘤内脱氧核糖核酸附近的生物硫醇;项目编号:51973082 61万,2020/01 - 2023/12;在研,主持。

3. 横向课题:具有市场应用价值的荧光材料的研发;70万,2022/04-2025/12; 在研,主持。

4. 国家自然科学基金青年项目,基于新型近红外荧光探针追踪癌细胞内核糖核酸(RNA)附近过氧化氢的动态变化研究,项目编号: 51503077 20万, 2016/01-2018/12,已结题。主持

5. 山东省自然科学基金, 构建新型近红外荧光探针追踪癌细胞内线粒体附近过氧化氢动态变化的研究,项目编号:ZR2015PE0016万,2015/07-2016/12, 已结题,主持。

6. 校级博士基金,基于咔唑类双光子功能材料的设计、合成及其对膜有序相的检测,项目编号:1600821025万, 2015 /7 -2016 / 12; 已结题:主持

六、主要成果

【代表性SCI论文

2022年成果-藻毒素及核酸识别与检测

1. Huixia Zhang, Bingyan Li, Yipeng Liu, Huiyan Chuan, Yong Liu*, Ping Xie*. Immunoassay technology: Research progress in microcystin-LR detection in water samples, Journal of Hazardous Materials, 2022, 424, 127406 (一区,IF=10.58).

2. Yipeng Liu, Bingyan Li, Huixia Zhang, Yong Liu*, Ping Xie*. Participation of fluorescence technology in the cross-disciplinary detection of microcystins. Coordin. Chem. Rev. 2022, 457, 214416. (一区,IF=22.315).

3. Zhaomin Wang, Congcong Wang, Tianhe Fang, Yong Liu*. Constructing a novel near-infrared fluorescent probe with a large Stokes shift for detection of RNA in the cancer cells. Dyes and Pigments, 2022, 200, 110126 (一区,IF=4.9)

4. Yipeng Liu, Bingyan Li, Huixia Zhang, Yong Liu*, Ping Xie*. Detection of Microcystin‑LR in the Cells and Natural Lake Water Samples by A Unique Fluorescence‑Based Method. J. Fluresc, 2022, 32, 505-519  (四区,IF=2.2).

 

2021年成果-藻毒素识别与检测

1. Bingyan Li, Yipeng Liu, Huixia Zhang, Yong Liu*, Ping Xie*. Research progress in the functionalization of microcystin-LR based on interdisciplinary technologies. Coordin. Chem. Rev. 2021, 443, 214041. (被引频次进入学术领域最优秀前0.1%;一区,IF=22.315).

发明专利:

1. 一种荧光探针的制备方法和应用,申请号:202110598007.8

2. 一种罗丹明类化合物的制备方法和在检测微囊藻毒素中的应用,申请号:20211136388403-已授权

3. 一种核糖核酸荧光探针及其制备方法和应用,申请号:202111464008.X,已授权

 

2016-2020年成果-检测

1.        Yong Liu, Jie Niu, Weishan Wang, Yanyan Ma and Weiying Lin, Simultaneous Imaging of Ribonucleic Acid and Hydrogen Sulfide in Living Systems with Distinct Fluorescence Signals Using a Single Fluorescent Probe. Advanced Science, 2018, 51700966 (IF =16.8)

2.        Yong Liu, Jie Niu, Weishan Wang and Weiying Lin, Tracking of Mitochondrial Endogenous Ribonucleic Acid in the Cancer Cells and Macrophages Using a Novel Small-Molecular Fluorescent Probe. Anal. Chem., 2019, 91, 1715-1718.  (IF =7.0)

3.        Yong Liu, Jing Nie, Jie Niu, Weishan Wang and Weiying Lin, An AIE + ESIPT ratiometric fluorescent probe for monitoring sulfur dioxide with distinct ratiometric fluorescence signals in mammalian cells, mouse embryonic fibroblast and zebrafish. J. Mater. Chem. B, 2018, 6, 1973-1983 IF =6.33

4.        Minggang Tian, Yong Liu, (共同一作), Yuming Sun, Ruoyao Zhang, Ruiqing Feng, Ge Zhang, Lifang Guo, Xuechen Li, Xiaoqiang Yu, JingZhi Sun, Xiuquan He, A Single Fluorescent Probe Enables Clearly Discriminating and Simultaneously Imaging Liquid-ordered and Liquid-disordered Microdomains in Plasma Membrane of Living Cells, Biomaterials, 2017, 120, 46-56. (IF =12.5)

5.        Yong Liu, Fangfang Meng, Longwei He, Xiaoqiang Yu and Weiying LinFluorescence behavior of a unique two-photon fluorescent probe in aggregate and solution states and highly sensitive detection of RNA in water solution and living systems, Chem. Commun., 2016, 52, 8838-8841.(IF=6.2).

6.        Yong Liu, Fangfang Meng, Longwei He, Keyin Liu and Weiying Lin*, A dual-site two-photon fluorescent probe for visualizing lysosomes and tracking lysosomal hydrogen sulfide with two different sets of fluorescence signals in the living cells and mouse liver tissues, Chem. Commun., 2016, 52, 7016-7019.(IF=6.2)

7.        Yong Liu, Fangfang Meng, Jing Nie, Jie Niu, Xiaoqiang Yu and Weiying Lin. Two-photon fluorescent probe for detecting cell membranal liquid-ordered phase by an aggregate fluorescence method, J. Mater. Chem. B, 2017, 5, 4725-4731. (IF=6.33)

8.        Yong Liu, Jie Niu , Weishan Wang , Baoli Dong and Weiying Lin. Unique phenanthrenequinone imidazole-based fluorescent materials with aggregation-induced or two-photon emission. J. Mater. Chem. B, 2017, 5, 7783-7900. ((IF=6.33前封面文章)

9.        Yong Liu, Jing Nie, Jie Niu, Fangfang Meng and Weiying Lin, Ratiometric fluorescent probe with AIE property for monitoring endogenous hydrogen peroxide in macrophages and cancer cells, Scientific Reports2017, 17293  (IF=4.38).

10.     Yong Liu, Jie Niu, Jing Nie, Fangfang Meng and Weiying Lin. A mitochondria-targetable fluorescent probe with a large Stokes shift for detecting hydrogen peroxide in aqueous solution and living cells. New. J. Chem., 2017, 41, 3320-3325. (IF=3.2).

11.     Yong Liu, Fangfang Meng and Weiying Lin, Single fluorescent probe for reversibly detecting copper ions and cysteine in a pure water system, RSC Adv., 2016, 6, 30951–30955.(IF=3.3).

12.     Yong Liu, Fangfang Meng, Yonghe Tang, Xiaoqiang Yu and Weiying Lin, A photostable fluorescent probe for rapid monitoring and tracking of a trans-membrane process and mitochondrial fission and fusion dynamics, New J. Chem., 2016, 40, 3726—3731. (IF=3.3).

13.     Yong Liu, Weijia Zhang, Yuming Sun, Guofen Song, Fang Miao and Xiaoqiang Yu, Two-photon fluorescence imaging of RNA in nucleoli and cytoplasm in living cells based on low molecular weight probes, Dyes and Pigments, 2014, 103, 191-201. (IF=4.9).

………

七、学生培养

●  招生专业:欢迎生态学、资源与环境类等相关专业学生加入我们团队。

 

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